Immunohistochemical techniques were used to observed the localization of paraquat in the
small intestine, liver and kidney, organs that absorb and eliminate chemicals. Paraquat-
poisoned rats were killed 3 h, 12 h, 24 h, 3 days and 10 days after intravenous
administration of paraquat. Three hours after injection, paraquat was localized in
hepatocytes and in the kidney in the epithelial cells of the distal tubule. The amount of
paraquat in the liver and kidney increased by 24 h after the administration and thereafter …